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INSM
ACCE-researched

Insmed Incorporated Common Stock (INSM) fair value

Healthcare · Biotechnology · NASDAQ · United States
$93.39-1.76%
Market cap $20.4BNext earnings 2026-10-29Updated Oct 16, 2026
Add earnings to calendarGoogle
Our verdict
Trades 22% below our fair value
Price
$93.39
Model fair valueConfidence: low
about $120
Built from weaker models, sales multiples or analyst targets, so treat it as a rough guide.
Not used by alerts or posts.
Valued as a loss-making company: Sales comps and Analyst consensus.
ACCE opinionInsmed Incorporated Common Stock (INSM)
Fair value
Not available
ACCE price target
$130
Rating
Not rated
Horizon
12 months
ACCE price target published on 24 Sept 2026, 00:00 CEST.
Price used: $93.39 at the close on 23 Oct 2026, 22:00 CEST.
Models: Analyst consensus and Sales comps.
Fair value: the average of the applicable valuation models (discounted cash flow, multiples, residual income, dividend discount, shareholder yield), each run on the latest financial statements and the market price shown. Opinion columns (fair value, target, rating) are shown apart from the data. Full methodology: acceinvestments.com/data/how-we-value-stocks
Full methodology
Conflicts of interest: The author holds no personal position in this security. General statement
Produced by ACCE Investments (acceinvestments.com)
Data
ACCE score
32
out of 100
Analysts
96% buy
24 covering
P/E
0.0x
forward 97.1x
1-year return
-41.7%
Dividend yield
0.00%

Insmed Incorporated Common Stock in four questions

Plain answers, details below
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OverviewAsk ACCEValuationQualityAnalystsSmart MoneyCompareNews and Record

Overview

ACCE thesis

Insmed sells ARIKAYCE, an inhaled antibiotic for refractory Mycobacterium avium complex lung disease, and its revenue is growing at 296% year over year, with an 83.5% gross margin. The moat is the product's narrow regulatory and clinical footprint in a hard-to-treat niche, though the company is still loss-making, with an operating margin of -23.8% and a return on equity of -87.2%. The near-term question is whether commercial scale-up can push operating losses toward breakeven before the balance sheet needs more capital. At a forward P/E of 127.2 the stock is priced for that transition to succeed. Our composite score is 32/100 and the name carries no index membership, so it is a candidate for a deeper look at the commercial trajectory rather than a finished case.

AI-assisted·How I use AIWritten Oct 13, 2026
⚠ Investor warnings · 4 flagsAI-assisted·How I use AI
  • high
    Massive negative free cash flow
    FCF of -$968M against $22B market cap signals the company is burning cash at an unsustainable rate despite 296% revenue growth.
  • high
    Deep unprofitability with margin deterioration
    Operating margin -23.8%, net margin -76.9%, ROE -87.2%. Company loses $0.77 per dollar of revenue; growth is not translating to profitability.
  • high
    Insider selling without offsetting buying
    Last 10 disclosures show $39.2M in insider sales and $0 in buys. Insiders are exiting while the stock trades near model fair value.
  • moderate
    ACCE score deterioration
    Score fell 7 points in 90 days (39 to 32). Quality and valuation scores remain weak (Q:38, V:10), signaling deteriorating fundamentals.

AI research notes

AI-assisted·How I use AIWritten Oct 11, 2026 · figures from 2026-06-30 · prices to Oct 23, 2026
Why it could do well
  • Revenue surged 296.1% year over year, showing brensocatib launch is gaining real commercial traction in market.
  • All 24 analysts rate the stock Buy or Strong Buy, with a mean price target 96.6% above current price.
  • Latest earnings beat expectations by 24.6%, suggesting the company is executing better than skeptics modeled.
Why it could disappoint
  • Free cash flow of negative 968 million dollars against debt to equity of 1.04 forces dilutive raises soon.
  • Forward P/E of 97.1x and negative 76.9% net margin mean the stock prices in perfection with no margin for error.
  • Share count jumped 30.2% last year while return on equity sits at negative 87.2%, destroying shareholder value.
Each chip shows the exact figure and where it comes from. A claim without a source is not published.

Next results

Oct 29, 2026
We update the fair value about 2 days after the results, once the new figures are filed.Add to calendarGoogle

Walk me through this stock

Plain-English pros, cons, and what to watch. Pro feature.

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Valuation

INVESTOR
Where INSM's valuation models land
Price
$93.39
Model fair valueConfidence: low
about $120
Model
Fair value
Upside
Analyst consensus
Sales comps
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Quality

INVESTOR
Quality and conviction INVESTOR FEATURE

The full quality picture: a reason under every score, how the scores moved, and the conviction breakdown.

  • +A plain reason under every score
  • +Conviction breakdown and growth / value / quality / momentum scores
  • +Score history: how each score moved over time

Analysts

Wall Street consensus

Bullish96% buy · 24 covering analysts
● Strong buy 18● Buy 5● Hold 1● Sell 0● Strong sell 0
Analyst intelligence INVESTOR FEATURE

The full analyst picture: the price-target distribution against the current price, forward consensus estimates, and how ACCE's own models compare.

  • +Price-target low / average / high vs the current price, with implied upside
  • +Forward revenue and EPS consensus by fiscal year
  • +ACCE fair-value models lined up against the Street

Smart Money

PRO

In one line

Trades are only made public after a delay. We show the delay so you know how old the news is.

Company insiders
No trades filed
Last 90 days
Congress
0 buys · 1 sell
Since Jun 10, 2026, 1 member
Average delay
27 days
From trade to public filing
Full trade list on ProDo politicians beat the market? Our backtest →
Smart money tracking PRO FEATURE

Follow the informed money: 13F position changes, insider and Congress trades, and 13D activist filings.

  • +Quarter-over-quarter institutional position changes
  • +Every insider and Congress trade, with how late it was disclosed
  • +Active 13D activist filings and top holders

Compare

Where it sits vs peers

News and Record

Press releases mentioning this company

Recent performance

1 week
-3.0%
1 month
-21.1%
3 months
-12.7%
6 months
-30.9%
YTD
-46.3%
1 year
-41.7%

SEC filings

Recommendation history, last 12 months

DateTypeNewPreviousPrice
24 Sept 2026, 00:00 CESTACCE price target$130first publication$121

This analysis is not personalised investment advice and does not take your situation, objectives or risk tolerance into account. ACCE Investments is not an authorised investment firm.

Investing in shares carries a risk of losing capital. The value of an investment can go down as well as up.

Valuation horizon: 12 months from the publication date.

Conflicts of interest. ACCE Investments is operated by Adrien Chantreuil, who may hold personal positions in the securities analysed. Positions are declared on each security. ACCE receives no payment from the companies analysed or from any intermediary for this analysis.

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Snapshot

Growth64Value10Quality38Momentum17Total32
Valuation
Trailing P/E
0.0x
Forward P/E
97.1x
PEG
1.09
P/B
34.83x
EV / Revenue
22.7x
Book value/sh
$3.47
Enterprise value
$25.8B
Profitability
ROE
-87.2%
FCF yield
-4.71%
ROIC
-69.5%
Health and risk
Debt / equity
1.04
Dividend yield
0.00%
Beta
0.82

Price

-41.5% · 1Y

Ask anything about INSM

Answered from Insmed Incorporated Common Stock fundamentals + recent valuations. Every number shows its source and date.

This stock Peer Peer median weaker → stronger
P/Ebetter than 100% of peers
low 0.0x0.0xhigh 108.1x
ROEbetter than 0% of peers
low -87%-87%high 119%
Div yieldbetter than 100% of peers
low 0.0%0.0%high 0.0%

Peers

Prices Oct 23, 2026
CompanyPriceFair valuevs fair valueP/EROEQualityScore
INSM Insmed Incorporated Common Stock$93.39----87.2%3832
BNTX BioNTech SE American Depositary Share$89.67----9.3%4732
1801.HK Innovent Biologics, Inc.HK$81.60HK$6232% above108.1x7.0%7159
INCY Incyte Corp. Common Stock$116.93$1133% above14.9x30.7%9692
GMAB.CO Genmab A/Skr 2654.00kr 354325% below32.7x14.0%7868
GMAB Genmab A/S ADS$40.00$5527% below31.3x14.0%7868
ASND Ascendis Pharma A/S American Depositary Shares$242.99--18.3x118.8%8263

Sector report card

Where INSM ranks against its sector peers on each metric.

Computing percentiles…
  • PR Newswire•Oct 19, 2026
    Insmed Launches BRINSUPRI® Tablets 25 mg (brensocatib hydrate) for the Treatment of Non-Cystic Fibrosis Bronchiectasis in Japan
  • PR Newswire•Oct 15, 2026
    Insmed Features the Global Phase 3 PALM Clinical Development Program Evaluating Treprostinil Palmitil Inhalation Powder (TPIP) at CHEST 2026
  • PR Newswire•Oct 14, 2026
    Insmed to Present New Data Across Its Respiratory Portfolio at CHEST 2026 and IDWeek 2026
8 more press releases · full archive on Investor+.INVESTOR
40 filings
October 2026
Oct 20
Form 4Insider transactionPeriod 2026-10-19
View on SEC →
Oct 20
Form 4Insider transactionPeriod 2026-10-19
View on SEC →
Oct 20
8-KCurrent reportPeriod 2026-10-16
View on SEC →
37 more filings + AI summaries on Investor+.INVESTOR