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GYRE

Gyre Therapeutics Inc. Common Stock (GYRE) fair value

Healthcare · Biotechnology · NASDAQ · United States
$5.85-0.17%
Market cap $620MNext earnings 2026-11-06Updated Oct 24, 2026
Add earnings to calendarGoogle
Our verdict
Trades 263% above our fair value
Price
$5.85
Model fair valueConfidence: good
$1.61
Model range
$1.46 to $1.90
Fair value $1.61
Price $5.85
2 models fit Gyre Therapeutics Inc. Common Stock and they agree: 2 of 2 land within 15% of the average. The price is above every model.
Two or more of our models back this value.
Large premium(i)
Valued as a growth company: Discounted cash flow and EV/EBITDA comparison.
ACCE opinionGyre Therapeutics Inc. Common Stock (GYRE)
Fair value (2 models)
$1.61
ACCE price target
$5.40
Rating
Overvalued
Horizon
12 months
Fair value published on 24 Oct 2026, 17:04 CEST; previously $2.00 since 17 Oct 2026, 00:00 CEST.
ACCE price target published on 14 Oct 2026, 00:00 CEST.
Rating published on 24 Oct 2026, 17:04 CEST.
Price used: $5.85 at the close on 23 Oct 2026, 22:00 CEST.
Models: Discounted cash flow and EV/EBITDA comparison.
Fair value: the average of the applicable valuation models (discounted cash flow, multiples, residual income, dividend discount, shareholder yield), each run on the latest financial statements and the market price shown. Opinion columns (fair value, target, rating) are shown apart from the data. Full methodology: acceinvestments.com/data/how-we-value-stocks
Full methodology
Conflicts of interest: The author holds no personal position in this security. General statement
Produced by ACCE Investments (acceinvestments.com)
Data
Price vs fair value
263.3% above
-72.5% to fair value
ACCE score
31
out of 100
Analysts
100% buy
3 covering
P/E
0.0x
forward 97.5x
1-year return
-28.9%
Dividend yield
0.00%

Gyre Therapeutics Inc. Common Stock in four questions

Plain answers, details below
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OverviewAsk ACCEValuationQualityAnalystsSmart MoneyCompareNews and Record

Overview

ACCE thesis

Gyre Therapeutics sells Envarsus XR, an extended-release tacrolimus tablet used to prevent organ rejection in transplant patients, and its margin profile reflects a product business with a 93.8% gross margin. The thesis rests on that product franchise and whether it can carry the company through a period of shrinking revenue. Revenue is declining 2.1% year over year, and operating margin sits at -47.6%, so the business is currently spending well beyond what it earns. The stock trades at a forward P/E of 188.7 against an ROE of -17.4%, which leaves little valuation support unless the revenue line stabilises. The name has a score of 32 out of 100 and no index membership, which fits a company where the question is still whether the franchise can return to growth, and that is the first thing to check before going further.

AI-assisted·How I use AIWritten Oct 18, 2026
⚠ Investor warnings · 3 flagsAI-assisted·How I use AI
  • high
    Revenue shrinking year over year
    Revenue fell 2.1% year over year despite a 41.0% five-year revenue CAGR, so recent top-line momentum has reversed.
  • high
    Heavy operating losses, thin cash
    Operating margin is -47.6% and free cash flow is $-180,000, so the company is burning cash with no reported profit to offset it.
  • moderate
    Insider ownership dominates float
    Insiders hold 74.4% of shares while institutions hold 8.2%, leaving a thin free float that can amplify price moves.

AI research notes

AI-assisted·How I use AIWritten Oct 21, 2026 · figures from 2026-06-30 · prices to Oct 23, 2026
Why it could do well
  • Analysts rate the stock Buy or Strong Buy, and their mean price target sits far above the current share price.
  • Revenue grew at a five-year average of +41.0% per year, showing the business has expanded quickly over time.
  • Debt to equity of 0.01 means the company carries almost no borrowings, leaving little balance sheet strain.
Why it could disappoint
  • Revenue fell 2.1% year over year, and free cash flow over the last 12 months was negative at -$180,000.
  • The latest earnings per share missed expectations by 50.0%, with a loss of -0.12 against -0.08 expected.
Each chip shows the exact figure and where it comes from. A claim without a source is not published.

Next results

Nov 6, 2026
We update the fair value about 2 days after the results, once the new figures are filed.Add to calendarGoogle

Walk me through this stock

Plain-English pros, cons, and what to watch. Pro feature.

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Valuation

INVESTOR
Where GYRE's valuation models land
Price
$5.85
Model fair value
$1.61
Model range
$1.46 to $1.90
Fair value $1.61
Price $5.85
The price is above the whole model range.
Model
Fair value
Upside
Discounted cash flow
EV/EBITDA comparison
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Quality

INVESTOR
Quality and conviction INVESTOR FEATURE

The full quality picture: a reason under every score, how the scores moved, and the conviction breakdown.

  • +A plain reason under every score
  • +Conviction breakdown and growth / value / quality / momentum scores
  • +Score history: how each score moved over time

Analysts

Wall Street consensus

Bullish100% buy · 3 covering analysts
● Strong buy 3● Buy 0● Hold 0● Sell 0● Strong sell 0
Analyst intelligence INVESTOR FEATURE

The full analyst picture: the price-target distribution against the current price, forward consensus estimates, and how ACCE's own models compare.

  • +Price-target low / average / high vs the current price, with implied upside
  • +Forward revenue and EPS consensus by fiscal year
  • +ACCE fair-value models lined up against the Street

Smart Money

PRO

In one line

Trades are only made public after a delay. We show the delay so you know how old the news is.

Company insiders
No trades filed
Last 90 days
Congress
No trades filed
Last 180 days
Average delay
No trades filed
From trade to public filing
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Smart money tracking PRO FEATURE

Follow the informed money: 13F position changes, insider and Congress trades, and 13D activist filings.

  • +Quarter-over-quarter institutional position changes
  • +Every insider and Congress trade, with how late it was disclosed
  • +Active 13D activist filings and top holders

Compare

Where it sits vs peers

News and Record

Press releases mentioning this company

Recent performance

1 week
-3.8%
1 month
-20.9%
3 months
-1.5%
6 months
-21.4%
YTD
-17.1%
1 year
-28.9%

SEC filings

Recommendation history, last 12 months

DateTypeNewPreviousPrice
24 Oct 2026, 17:04 CESTFair value$1.61$2.00$5.85
24 Oct 2026, 17:04 CESTRatingOvervaluedfirst publication$5.85
17 Oct 2026, 00:00 CESTFair value$2.00$1.69$6.40
14 Oct 2026, 00:00 CESTACCE price target$5.40first publication$6.71
8 Oct 2026, 00:00 CESTFair value$1.69$1.75$7.08
5 Oct 2026, 00:00 CESTFair value$1.75$1.72$7.11
1 Oct 2026, 00:00 CESTFair value$1.72$1.76$7.32
23 Sept 2026, 00:00 CESTFair value$1.76$1.87$7.43
20 Sept 2026, 00:00 CESTFair value$1.87$1.78$7.55
15 Sept 2026, 00:00 CESTFair value$1.78$1.76$6.73

This analysis is not personalised investment advice and does not take your situation, objectives or risk tolerance into account. ACCE Investments is not an authorised investment firm.

Investing in shares carries a risk of losing capital. The value of an investment can go down as well as up.

Valuation horizon: 12 months from the publication date.

Conflicts of interest. ACCE Investments is operated by Adrien Chantreuil, who may hold personal positions in the securities analysed. Positions are declared on each security. ACCE receives no payment from the companies analysed or from any intermediary for this analysis.

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Snapshot

Growth43Value16Quality47Momentum17Total31
Valuation
Trailing P/E
0.0x
Forward P/E
97.5x
PEG
no data
P/B
6.56x
EV / Revenue
5.8x
Book value/sh
$1.02
Enterprise value
$639M
Profitability
ROE
-17.4%
FCF yield
-0.03%
ROIC
3.9%
Health and risk
Debt / equity
0.01
Dividend yield
0.00%
Beta
4.74

Price

-27.1% · 1Y

Ask anything about GYRE

Answered from Gyre Therapeutics Inc. Common Stock fundamentals + recent valuations. Every number shows its source and date.

This stock Peer Peer median weaker → stronger
P/Ebetter than 100% of peers
low 0.0x0.0xhigh 252.1x
ROEbetter than 0% of peers
low -17%-17%high 16%
Div yieldbetter than 67% of peers
low 0.0%0.0%high 0.7%

Peers

Prices Oct 23, 2026
CompanyPriceFair valuevs fair valueP/EROEQualityScore
GYRE Gyre Therapeutics Inc. Common Stock$5.85$2263% above--17.4%4731
ZEAL.CO Zealand Pharma A/Skr 226.00--5.7x16.3%9051
BIOA-B.ST BioArctic AB (publ)kr 300.00kr 25916% above252.1x5.2%6240
BAVA.CO Bavarian Nordic A/Skr 247.40kr 37835% below12.7x12.2%8686
CAMX.ST Camurus AB (publ)kr 666.00kr 325105% above58.8x15.9%9058
BIOCON.NS Biocon Limited₹323.50--95.7x-6751
CORT Corcept Therapeutics Incorporated Common Stock$85.86$40117% above238.5x8.2%7572

Sector report card

Where GYRE ranks against its sector peers on each metric.

Computing percentiles…
  • GlobeNewswire•Sep 3, 2026
    Gyre Therapeutics to Participate in Upcoming September Investor Conferences
  • GlobeNewswire•Aug 7, 2026
    Gyre Therapeutics Reports Second Quarter 2026 and Year-to-Date Financial Results and Provides Business Update
  • GlobeNewswire•Jul 16, 2026
    Gyre Therapeutics Appoints Three New Members to its Board of Directors
3 more press releases · full archive on Investor+.INVESTOR
40 filings
October 2026
Oct 22
8-KCurrent reportPeriod 2026-10-16
View on SEC →
September 2026
Sep 1
8-KCurrent reportPeriod 2026-09-01
View on SEC →
August 2026
Aug 26
8-KCurrent reportPeriod 2026-08-26
View on SEC →
37 more filings + AI summaries on Investor+.INVESTOR