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CRBU
ACCE-researched

Caribou Biosciences Inc. Common Stock (CRBU) fair value

Healthcare · Biotechnology · NASDAQ · United States
$0.53-4.86%
Market cap $57MNext earnings 2026-11-11Updated Oct 24, 2026
Add earnings to calendarGoogle
Our verdict
Trades 51% below our fair value
Price
$0.53
Model fair valueConfidence: low
about $1.08
Built from weaker models, sales multiples or analyst targets, so treat it as a rough guide.
Not used by alerts or posts.
Treated as a loss-making company. None of the usual models had enough data, so this uses Net asset value instead.
ACCE opinionCaribou Biosciences Inc. Common Stock (CRBU)
Fair value
Not available
ACCE price target
$0.48
Rating
Not rated
Horizon
12 months
ACCE price target published on 9 Oct 2026, 00:00 CEST.
Price used: $0.53 at the close on 23 Oct 2026, 22:00 CEST.
Models: Net asset value.
Fair value: the average of the applicable valuation models (discounted cash flow, multiples, residual income, dividend discount, shareholder yield), each run on the latest financial statements and the market price shown. Opinion columns (fair value, target, rating) are shown apart from the data. Full methodology: acceinvestments.com/data/how-we-value-stocks
Full methodology
Conflicts of interest: The author holds no personal position in this security. General statement
Produced by ACCE Investments (acceinvestments.com)
Data
ACCE score
17
out of 100
Analysts
33% buy
6 covering
P/E
0.0x
forward 0.0x
1-year return
-78.8%
Dividend yield
0.00%

Caribou Biosciences Inc. Common Stock in four questions

Plain answers, details below
Free accounts get 5 full stock pages a month, including the four answers.
OverviewAsk ACCEValuationQualityAnalystsSmart MoneyCompareNews and Record

Overview

ACCE thesis

Caribou Biosciences develops CRISPR-based gene editing platforms for allogeneic (off-the-shelf) cell therapies, including its CB-010 CAR-T program in oncology and CB-011 in multiple myeloma. The platform is the asset: a proprietary editing toolkit that could in principle let one donor cell product serve many patients, a structural advantage over autologous therapies if clinical data hold. The next catalysts are clinical readouts and any partnership milestones, but the company is still burning cash against a revenue base that fell 43.8% in the latest period, with an operating margin of -1690.4%, so the balance sheet and funding runway matter more than the science for the near term. At a $50M market cap the equity prices in a high probability of dilution or restructuring, and the 18/100 score reflects that. The name merits a deeper look only if you have a view on the clinical timeline and the cash runway, since the financials alone do not make the case.

AI-assisted·How I use AIWritten Oct 18, 2026
⚠ Investor warnings · 4 flagsAI-assisted·How I use AI
  • severe
    Cash burn and negative FCF
    Annual FCF of -$59.6M against $49M market cap signals runway crisis. Company burning cash at rate exceeding annual valuation.
  • severe
    Revenue collapse and operating losses
    Revenue down 43.8% YoY and 37.5% QoQ. Operating margin -1690.4% indicates massive operating losses relative to sales.
  • high
    Score deterioration and insider selling
    ACCE score fell 8 points in 90 days (30 to 22). Insiders sold $0.08M with zero buys; no confidence signal.
  • high
    Negative equity and ROE collapse
    ROE of -78.3% and net margin 0.0% suggest equity is eroding. Debt/Equity 0.27 may understate distress if equity is negative.

AI research notes

AI-assisted·How I use AIWritten Oct 11, 2026 · figures from 2026-06-30 · prices to Oct 23, 2026
Why it could do well
  • The company beat earnings expectations by 27.3%, suggesting execution is better than feared.
  • One third of analysts rate the stock Buy or Strong Buy, and debt to equity of 0.27 is manageable.
Why it could disappoint
  • Revenue fell 43.8% year over year and has declined 7.0% annually over five years.
  • Negative free cash flow of $60M in the last 12 months yields a negative 120.8% free cash flow yield.
  • Return on equity of negative 78.3% and return on invested capital of negative 98.4% show capital destruction.
Each chip shows the exact figure and where it comes from. A claim without a source is not published.

Next results

Nov 11, 2026
We update the fair value about 2 days after the results, once the new figures are filed.Add to calendarGoogle

Walk me through this stock

Plain-English pros, cons, and what to watch. Pro feature.

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Valuation

INVESTOR
Where CRBU's valuation models land
Price
$0.53
Model fair valueConfidence: low
about $1.08
Model
Fair value
Upside
Net asset value
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See what each model says, the assumptions behind it, the bad, normal and good cases, and why the fair value changed.

Quality

INVESTOR
Quality and conviction INVESTOR FEATURE

The full quality picture: a reason under every score, how the scores moved, and the conviction breakdown.

  • +A plain reason under every score
  • +Conviction breakdown and growth / value / quality / momentum scores
  • +Score history: how each score moved over time

Analysts

Wall Street consensus

Bearish33% buy · 6 covering analysts
● Strong buy 2● Buy 0● Hold 4● Sell 0● Strong sell 0
Analyst intelligence INVESTOR FEATURE

The full analyst picture: the price-target distribution against the current price, forward consensus estimates, and how ACCE's own models compare.

  • +Price-target low / average / high vs the current price, with implied upside
  • +Forward revenue and EPS consensus by fiscal year
  • +ACCE fair-value models lined up against the Street

Smart Money

PRO

In one line

Trades are only made public after a delay. We show the delay so you know how old the news is.

Company insiders
No trades filed
Last 90 days
Congress
No trades filed
Last 180 days
Average delay
No trades filed
From trade to public filing
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Smart money tracking PRO FEATURE

Follow the informed money: 13F position changes, insider and Congress trades, and 13D activist filings.

  • +Quarter-over-quarter institutional position changes
  • +Every insider and Congress trade, with how late it was disclosed
  • +Active 13D activist filings and top holders

Compare

Where it sits vs peers

News and Record

Press releases mentioning this company

Recent performance

1 week
+12.8%
1 month
-58.9%
3 months
-66.2%
6 months
-75.1%
YTD
-66.7%
1 year
-78.8%

SEC filings

Recent ACCE blog coverage

  • $CRBU Score Jumps 44 Points to 49 on ACCE Composite Rating
    Caribou Biosciences sees major ACCE score improvement from 5 to 49, suggesting significant changes in fundamental or technical metrics.
    2026-05-06

Recommendation history, last 12 months

DateTypeNewPreviousPrice
9 Oct 2026, 00:00 CESTACCE price target$0.48first publication$0.48

This analysis is not personalised investment advice and does not take your situation, objectives or risk tolerance into account. ACCE Investments is not an authorised investment firm.

Investing in shares carries a risk of losing capital. The value of an investment can go down as well as up.

Valuation horizon: 12 months from the publication date.

Conflicts of interest. ACCE Investments is operated by Adrien Chantreuil, who may hold personal positions in the securities analysed. Positions are declared on each security. ACCE receives no payment from the companies analysed or from any intermediary for this analysis.

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Snapshot

Growth7Value11Quality31Momentum17Total17
Valuation
Trailing P/E
0.0x
Forward P/E
0.0x
PEG
no data
P/B
1.25x
EV / Revenue
5.4x
Book value/sh
$0.93
Enterprise value
$50M
Profitability
ROE
-78.3%
FCF yield
-187.14%
ROIC
-81.3%
Health and risk
Debt / equity
0.22
Dividend yield
0.00%
Beta
2.31

Price

-78.4% · 1Y

Ask anything about CRBU

Answered from Caribou Biosciences Inc. Common Stock fundamentals + recent valuations. Every number shows its source and date.

This stock Peer Peer median weaker → stronger
P/Ebetter than 100% of peers
low 0.0x0.0xhigh 252.1x
ROEbetter than 0% of peers
low -78%-78%high 16%
Div yieldbetter than 67% of peers
low 0.0%0.0%high 0.7%

Peers

Prices Oct 23, 2026
CompanyPriceFair valuevs fair valueP/EROEQualityScore
CRBU Caribou Biosciences Inc. Common Stock$0.53----78.3%3117
ZEAL.CO Zealand Pharma A/Skr 226.00--5.7x16.3%9051
BIOA-B.ST BioArctic AB (publ)kr 300.00kr 25916% above252.1x5.2%6238
BAVA.CO Bavarian Nordic A/Skr 247.40kr 37835% below12.7x12.2%8686
CAMX.ST Camurus AB (publ)kr 666.00kr 325105% above58.8x15.9%9055
BIOCON.NS Biocon Limited₹323.50--95.7x-6752
CORT Corcept Therapeutics Incorporated Common Stock$85.86$40117% above238.5x8.2%7573

Sector report card

Where CRBU ranks against its sector peers on each metric.

Computing percentiles…
  • GlobeNewswire•Oct 6, 2026
    Caribou Biosciences to Evaluate Strategic Alternatives
  • GlobeNewswire•Aug 13, 2026
    Caribou Biosciences Reports Second Quarter 2026 Financial Results and Provides Business Update
  • GlobeNewswire•Jun 29, 2026
    Caribou Biosciences to Participate in the H.C. Wainwright 4th Annual Cell Therapy Virtual Conference
7 more press releases · full archive on Investor+.INVESTOR
28 filings of 35
October 2026
Oct 6
8-KCurrent reportPeriod 2026-10-02
View on SEC →
August 2026
Aug 13
8-KCurrent reportPeriod 2026-08-13
View on SEC →
Aug 13
10-QQuarterly reportPeriod 2026-06-30
View on SEC →
25 more filings + AI summaries on Investor+.INVESTOR