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NBIX
ACCE-researched

Neurocrine Biosciences Inc. Common Stock (NBIX) fair value

Healthcare · Drug Manufacturers - Specialty & Generic · NASDAQ · United States
$142.70-0.41%
Market cap $14.6BNext earnings 2026-11-02Updated Oct 19, 2026
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Our verdict
Close to our fair value
Price
$142.70
Model fair valueConfidence: good
$138
Model range
$74.20 to $246
Fair value $138
Price $143
3 models fit Neurocrine Biosciences Inc. Common Stock and they disagree: 0 of 3 land within 15% of the average.
Two or more of our models back this value.
Near fair value(i)Silver76
Valued as a growth company: Discounted cash flow, P/E comparison, and EV/EBITDA comparison.
ACCE opinionNeurocrine Biosciences Inc. Common Stock (NBIX)
Fair value (3 models)
$138
ACCE price target
$179
Rating
Fairly valued
Horizon
12 months
Fair value published on 19 Oct 2026, 19:04 CEST; previously $193 since 15 Oct 2026, 00:00 CEST.
ACCE price target published on 26 Sept 2026, 00:00 CEST.
Rating published on 19 Oct 2026, 19:04 CEST.
Price used: $143 at the close on 23 Oct 2026, 22:00 CEST.
Models: Discounted cash flow, P/E comparison, and EV/EBITDA comparison.
Fair value: the average of the applicable valuation models (discounted cash flow, multiples, residual income, dividend discount, shareholder yield), each run on the latest financial statements and the market price shown. Opinion columns (fair value, target, rating) are shown apart from the data. Full methodology: acceinvestments.com/data/how-we-value-stocks
Full methodology
Conflicts of interest: The author holds no personal position in this security. General statement
Produced by ACCE Investments (acceinvestments.com)
Data
Price vs fair value
3.6% above
-3.5% to fair value
ACCE score
79
out of 100
Analysts
86% buy
29 covering
P/E
20.7x
forward 14.1x
1-year return
-0.7%
Dividend yield
0.00%

Neurocrine Biosciences Inc. Common Stock in four questions

Plain answers, details below
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OverviewAsk ACCEValuationQualityAnalystsSmart MoneyCompareNews and Record

Overview

ACCE thesis

Neurocrine Biosciences develops and sells neuroscience drugs, with its core franchise built on Ingrezza, a treatment for tardive dyskinesia, and Crenessity, a therapy for congenital adrenal hyperplasia. The company has a durable edge in CNS (central nervous system) commercialization, where specialist prescriber relationships and long-dated patent protection make share hard for competitors to take. Revenue growth of 39.5% is the headline, and the near-term driver is continued uptake of Crenessity alongside Ingrezza's established base, with operating margin at 22.2% and gross margin at 64.5% indicating the mix is shifting toward high-margin product sales. At a trailing P/E of 19.8 against a forward P/E of 11.2, the market is pricing in a steep earnings ramp, so the question for the deeper work is whether that ramp is as durable as the forward multiple implies. With a 22.1% ROE and a 13.7B market cap, the name is worth a closer look on the durability of Crenessity uptake and Ingrezza's exposure to competition and pricing pressure.

AI-assisted·How I use AIWritten Oct 14, 2026
⚠ Investor warnings · 2 flagsAI-assisted·How I use AI
  • moderate
    ACCE score decline
    Score fell 3 points to 79 over 90 days, driven by momentum (M:61) weakness. Valuation (V:64) also lags, signaling recent market skepticism despite strong fundamentals.
  • moderate
    Insider selling signal
    Last 10 disclosures show $0.49M in sales with zero buys. Absence of insider accumulation at current valuations is a mild caution flag, though not severe given strong cash generation.

AI research notes

AI-assisted·How I use AIWritten Oct 16, 2026 · figures from 2026-10-10 · prices to Oct 23, 2026
Why it could do well
  • Revenue grew 39.5% year over year with a 24.3% five-year average, showing sustained expansion well above sector norms.
  • Net margin of 20.9% and ROE of 22.1% demonstrate efficient operations, while consensus values the stock 73.7% above current price.
Why it could disappoint
  • The reverse DCF implies only 5.8% perpetual cash flow growth, well below historical rates and insufficient to justify current valuation.
  • Free cash flow yield of 4.4% barely exceeds the 5.2% risk-free rate, offering minimal equity risk premium for biotech concentration risk.
  • Analyst consensus of 73.7% upside depends on pipeline success, yet the stock already prices in only 5.8% growth, leaving little margin for error.
Each chip shows the exact figure and where it comes from. A claim without a source is not published.

Next results

Nov 2, 2026
We update the fair value about 2 days after the results, once the new figures are filed.Add to calendarGoogle

Walk me through this stock

Plain-English pros, cons, and what to watch. Pro feature.

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Valuation

INVESTOR
Where NBIX's valuation models land
Price
$142.70
Model fair value
$138
Model range
$74.20 to $246
Fair value $138
Price $143
The price sits inside the model range.
Model
Fair value
Upside
Discounted cash flow
EV/EBITDA comparison
P/E comparison
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Quality

INVESTOR
Quality and conviction INVESTOR FEATURE

The full quality picture: a reason under every score, how the scores moved, and the conviction breakdown.

  • +A plain reason under every score
  • +Conviction breakdown and growth / value / quality / momentum scores
  • +Score history: how each score moved over time

Analysts

Wall Street consensus

Bullish86% buy · 29 covering analysts
● Strong buy 21● Buy 4● Hold 4● Sell 0● Strong sell 0
Analyst intelligence INVESTOR FEATURE

The full analyst picture: the price-target distribution against the current price, forward consensus estimates, and how ACCE's own models compare.

  • +Price-target low / average / high vs the current price, with implied upside
  • +Forward revenue and EPS consensus by fiscal year
  • +ACCE fair-value models lined up against the Street

Smart Money

PRO

In one line

Trades are only made public after a delay. We show the delay so you know how old the news is.

Company insiders
No trades filed
Last 90 days
Congress
No trades filed
Last 180 days
Average delay
No trades filed
From trade to public filing
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Smart money tracking PRO FEATURE

Follow the informed money: 13F position changes, insider and Congress trades, and 13D activist filings.

  • +Quarter-over-quarter institutional position changes
  • +Every insider and Congress trade, with how late it was disclosed
  • +Active 13D activist filings and top holders

Compare

Where it sits vs peers

News and Record

Press releases mentioning this company

Recent performance

1 week
+5.2%
1 month
+2.3%
3 months
-18.8%
6 months
+11.8%
YTD
+0.6%
1 year
-0.7%

SEC filings

Recommendation history, last 12 months

DateTypeNewPreviousPrice
19 Oct 2026, 19:04 CESTFair value$138$193$136
19 Oct 2026, 19:04 CESTRatingFairly valuedfirst publication$136
15 Oct 2026, 00:00 CESTFair value$193$247$135
11 Oct 2026, 00:00 CESTFair value$247$126$142
1 Oct 2026, 00:00 CESTFair value$126$127$138
26 Sept 2026, 00:00 CESTACCE price target$179first publication$138
26 Sept 2026, 00:00 CESTFair value$127$128$139
19 Sept 2026, 00:00 CESTFair value$128$257$152
17 Sept 2026, 00:00 CESTFair value$257$264$150
14 Sept 2026, 00:00 CESTFair value$264$133$156

This analysis is not personalised investment advice and does not take your situation, objectives or risk tolerance into account. ACCE Investments is not an authorised investment firm.

Investing in shares carries a risk of losing capital. The value of an investment can go down as well as up.

Valuation horizon: 12 months from the publication date.

Conflicts of interest. ACCE Investments is operated by Adrien Chantreuil, who may hold personal positions in the securities analysed. Positions are declared on each security. ACCE receives no payment from the companies analysed or from any intermediary for this analysis.

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Snapshot

Growth100Value71Quality91Momentum54Total79
Valuation
Trailing P/E
20.7x
Forward P/E
14.1x
PEG
0.28
P/B
3.90x
EV / Revenue
4.3x
Book value/sh
$36.35
Enterprise value
$14.4B
Profitability
ROE
22.1%
FCF yield
5.14%
ROIC
10.7%
Health and risk
Debt / equity
0.13
Dividend yield
0.00%
Beta
0.40

Price

-0.9% · 1Y

Ask anything about NBIX

Answered from Neurocrine Biosciences Inc. Common Stock fundamentals + recent valuations. Every number shows its source and date.

This stock Peer Peer median weaker → stronger
P/Ebetter than 83% of peers
low 9.8x20.7xhigh 118.3x
ROEbetter than 100% of peers
low 3%22%high 22%
Div yieldbetter than 17% of peers
low 0.0%0.0%high 2.5%

Peers

Prices Oct 23, 2026
CompanyPriceFair valuevs fair valueP/EROEQualityScore
NBIX Neurocrine Biosciences Inc. Common Stock$142.70$1384% above20.7x22.1%9179
IPN.PA Ipsen S.A.€152.20€18618% below24.5x11.4%7973
SOBI.ST Swedish Orphan Biovitrum AB (publ)kr 452.00kr 37820% above118.3x3.4%6773
4507.T Shionogi & Co., Ltd.¥3028.00--9.8x16.8%7872
ZYDUSLIFE.NS Zydus Lifesciences Limited₹1135.00--25.2x-8565
TORNTPHARM.NS Torrent Pharmaceuticals Limited₹4615.30--72.3x-7957
CIPLA.NS Cipla Limited₹1330.90--31.9x-8550

Sector report card

Where NBIX ranks against its sector peers on each metric.

Computing percentiles…
  • PR Newswire•Oct 12, 2026
    Neurocrine Biosciences Announces Conference Call and Webcast of Third Quarter 2026 Financial Results
  • PR Newswire•Sep 30, 2026
    Neurocrine Biosciences to Present Research Advancing Understanding of Prader-Willi Syndrome and Real-World Experience with VYKAT® XR (diazoxide choline) at Foundation for Prader-Willi Research Symposium & Family Conference
  • PR Newswire•Sep 28, 2026
    Neurocrine Biosciences Appoints Eiry W. Roberts, M.D., as Chief Medical Officer
6 more press releases · full archive on Investor+.INVESTOR
40 filings
September 2026
Sep 28
8-KCurrent reportPeriod 2026-09-25
View on SEC →
Sep 15
Form 4Insider transactionPeriod 2026-09-11
View on SEC →
Sep 15
Form 4Insider transactionPeriod 2026-09-11
View on SEC →
37 more filings + AI summaries on Investor+.INVESTOR