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APGE

Apogee Therapeutics Inc. Common Stock (APGE) fair value

Healthcare · Biotechnology · NASDAQ · United States
$135.07+0.00%
Market cap $10.2BNext earnings 2026-08-10Updated Oct 17, 2026
Our verdict
Close to our fair value
Price
$135.07
Model fair valueConfidence: low
about $135
Built from weaker models, sales multiples or analyst targets, so treat it as a rough guide.
Not used by alerts or posts.
Valued as a pre-revenue company: Analyst consensus.
ACCE opinionApogee Therapeutics Inc. Common Stock (APGE)
Fair value
Not available
ACCE price target
$125
Rating
Not rated
Horizon
12 months
ACCE price target published on 10 Oct 2026, 00:00 CEST.
Price used: $135 at the close on 11 Sept 2026, 22:00 CEST.
Models: Analyst consensus.
Fair value: the average of the applicable valuation models (discounted cash flow, multiples, residual income, dividend discount, shareholder yield), each run on the latest financial statements and the market price shown. Opinion columns (fair value, target, rating) are shown apart from the data. Full methodology: acceinvestments.com/data/how-we-value-stocks
Full methodology
Conflicts of interest: The author holds no personal position in this security. General statement
Produced by ACCE Investments (acceinvestments.com)
Data
ACCE score
40
out of 100
Analysts
100% buy
9 covering
P/E
0.0x
forward 0.0x
1-year return
+262.4%

Apogee Therapeutics Inc. Common Stock in four questions

Plain answers, details below
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OverviewAsk ACCEValuationQualityAnalystsSmart MoneyCompareNews and Record

Overview

ACCE thesis

Apogee is a clinical-stage biotech developing long-acting antibody therapies for inflammatory skin disease, led by APG777 for atopic dermatitis, a drug built to be dosed far less often than current biologics. With no revenue (0.0% growth, 0.0% gross margin) and an ROE of -32.5%, the equity is a pure bet on clinical and regulatory outcomes rather than on earnings, so the case rests entirely on pipeline data. A $10.2B market cap for a company with no product sales prices in substantial success, which makes the question for the deeper look whether the upcoming readouts and dosing data can support that valuation. The 40/100 composite score and absence from any index suggest the market and quantitative screens are not yet rewarding the story, so the work is to decide whether the trial evidence justifies the gap.

AI-assisted·How I use AIWritten Oct 18, 2026
⚠ Investor warnings · 3 flagsAI-assisted·How I use AI
  • moderate
    Cash burn with no revenue
    Free cash flow is -$232.6M and operating margin is 0.0%, with no revenue growth to offset the burn. Funding depends on existing cash and future raises.
  • moderate
    Insider selling, no buying
    Insiders sold $14.74M across the last 10 disclosed transactions and bought nothing. Insider ownership is only 2.3%.
  • moderate
    Earnings miss
    Latest quarter (Q3 2026) EPS came in 3.6% below expectations. Forward P/E of -26.0 reflects continued losses.

AI research notes

AI-assisted·How I use AIWritten Oct 15, 2026 · figures from 2026-06-30 · prices to Sep 11, 2026
Why it could do well
  • Nine of nine analysts rate the stock Buy or Strong Buy, a unanimous show of conviction from the Street.
  • Debt is almost nonexistent, with debt to equity at 0.01, so the company is not burdened by borrowing.
  • Earnings per share came in at -1.14 against -1.10 expected, a small miss that leaves the operating picture broadly intact.
Why it could disappoint
  • Free cash flow over the last twelve months was negative $233M, meaning the business is consuming cash rather than generating it.
  • Return on equity of -32.5% shows shareholder capital is being eroded, not compounded, by current operations.
  • The share count rose 10.0% in the last fiscal year, diluting existing holders' stake in the company.
Each chip shows the exact figure and where it comes from. A claim without a source is not published.

Walk me through this stock

Plain-English pros, cons, and what to watch. Pro feature.

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Valuation

INVESTOR
Where APGE's valuation models land
Price
$135.07
Model fair valueConfidence: low
about $135
Model
Fair value
Upside
Analyst consensus
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Quality

INVESTOR
Quality and conviction INVESTOR FEATURE

The full quality picture: a reason under every score, how the scores moved, and the conviction breakdown.

  • +A plain reason under every score
  • +Conviction breakdown and growth / value / quality / momentum scores
  • +Score history: how each score moved over time

Analysts

Wall Street consensus

Bullish100% buy · 9 covering analysts
● Strong buy 9● Buy 0● Hold 0● Sell 0● Strong sell 0
Analyst intelligence INVESTOR FEATURE

The full analyst picture: the price-target distribution against the current price, forward consensus estimates, and how ACCE's own models compare.

  • +Price-target low / average / high vs the current price, with implied upside
  • +Forward revenue and EPS consensus by fiscal year
  • +ACCE fair-value models lined up against the Street

Smart Money

PRO

In one line

Trades are only made public after a delay. We show the delay so you know how old the news is.

Company insiders
No trades filed
Last 90 days
Congress
No trades filed
Last 180 days
Average delay
No trades filed
From trade to public filing
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Smart money tracking PRO FEATURE

Follow the informed money: 13F position changes, insider and Congress trades, and 13D activist filings.

  • +Quarter-over-quarter institutional position changes
  • +Every insider and Congress trade, with how late it was disclosed
  • +Active 13D activist filings and top holders

Compare

Where it sits vs peers

News and Record

Press releases mentioning this company

Recent performance

1 week
+0.0%
1 month
+0.4%
3 months
+52.9%
6 months
+87.9%
YTD
+78.9%
1 year
+262.4%

SEC filings

Recommendation history, last 12 months

DateTypeNewPreviousPrice
10 Oct 2026, 00:00 CESTACCE price target$125first publication$135

This analysis is not personalised investment advice and does not take your situation, objectives or risk tolerance into account. ACCE Investments is not an authorised investment firm.

Investing in shares carries a risk of losing capital. The value of an investment can go down as well as up.

Valuation horizon: 12 months from the publication date.

Conflicts of interest. ACCE Investments is operated by Adrien Chantreuil, who may hold personal positions in the securities analysed. Positions are declared on each security. ACCE receives no payment from the companies analysed or from any intermediary for this analysis.

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Snapshot

Growth7Value23Quality31Momentum97Total40
Valuation
Trailing P/E
0.0x
Forward P/E
0.0x
PEG
no data
P/B
8.56x
EV / Revenue
0.0x
Book value/sh
$15.91
Enterprise value
$9.3B
Profitability
ROE
-32.5%
FCF yield
-2.28%
ROIC
-23.0%
Health and risk
Debt / equity
0.01
Dividend yield
no data
Beta
0.33

Price

+153.3% · 1Y

Ask anything about APGE

Answered from Apogee Therapeutics Inc. Common Stock fundamentals + recent valuations. Every number shows its source and date.

This stock Peer Peer median weaker → stronger
P/Ebetter than 100% of peers
low 0.0x0.0xhigh 153.1x
ROEbetter than 33% of peers
low -53%-32%high 20%

Peers

Prices Sep 11, 2026
CompanyPriceFair valuevs fair valueP/EROEQualityScore
APGE Apogee Therapeutics Inc. Common Stock$135.07----32.5%3140
MDGL Madrigal Pharmaceuticals Inc. Common Stock$453.34----53.3%4340
PCVX Vaxcyte Inc. Common Stock$62.85----36.5%3136
BMRN BioMarin Pharmaceutical Inc. Common Stock$56.63$4525% above153.1x1.2%6356
KRYS Krystal Biotech Inc. Common Stock$320.13$153110% above40.1x20.1%9571
KYMR Kymera Therapeutics Inc. Common Stock$110.85----24.1%3151
1177.HK Sino Biopharmaceutical LimitedHK$4.98HK$420% above33.3x14.1%8055

Sector report card

Where APGE ranks against its sector peers on each metric.

Computing percentiles…
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10 more press releases · full archive on Investor+.INVESTOR
40 filings
September 2026
Sep 3
8-KCurrent reportPeriod 2026-09-03
View on SEC →
Sep 3
Form 4Insider transactionPeriod 2026-09-03
View on SEC →
Sep 3
Form 4Insider transactionPeriod 2026-09-03
View on SEC →
37 more filings + AI summaries on Investor+.INVESTOR